In Vivo Scientist

In Vivo Scientist – Cell Therapy and Neurodegeneration

The Company

Mangrove Neuro (LIC, NY) is a well-funded, fast-paced, early-stage biotech company using cell and tissue replacement therapies to treat neurodegeneration and brain trauma. We use a multifaceted approach to designing and testing our prototypes. As an early-stage team member, your data will directly drive our upcoming IND-enabling milestones

The Role

We are seeking a highly motivated, cross-functional In Vivo Scientist to lead the validation of our neural graft prototypes in rodent models. You will oversee the end-to-end surgical, histological, and analytical pipelines, acting as a crucial bridge between our stem cell engineering team and pre-clinical milestones.

Key Responsibilities

- Perform survival stereotaxic surgical procedures in rodents, including graft preparation, tissue harvest, and transplantation.

- Image grafts by confocal and widefield microscopy and quantify cell survival, integration, and phenotype

- Maintain detailed experimental records and contribute to study design and IND-enabling documentation

Qualifications

- PhD with a background in neuroscience, neurodevelopment, stem cell biology, or related fields with 0-2 years of relevant post graduate experience (industry setting preferred)

- Hands-on experience with histology, immunostaining, and fluorescence microscopy

- Rodent brain survival surgery experience

- Ability to work independently and manage multiple experiments in a fast-paced, early-stage setting

- Experience using rodent stroke models and/or behavioral models

- Hands on experience with rat models

- Experience with hiPSC culture

- Quantitative image analysis (Fiji/ImageJ, QuPath, or similar)

- Familiarity with cell therapy development

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Compensation: $110,000 – 135,000 based on experience with great health insurance and equity.

Please apply through this portal or send your CV to Sign in to view email with “In Vivo Scientist application” in the subject line.