Bioprocess Associate 2 – Upstream

Aruna Bio | Manufacturing / Bioprocessing

Aruna Bio is a clinical-stage biotech company advancing a new class of cell-free biologics — exosomes — for the treatment of central nervous system and neurodegenerative disorders. We're looking for a Bioprocess Associate 2 – Upstream to join our manufacturing team and support production of AB126, our lead therapeutic exosome candidate.

As an Upstream Bioprocess Associate 2, you'll be executing established upstream production processes in a cGMP environment, as well as contributing to the planning and procurement for future productions. We need someone with strong hands-on cell culture skills, disciplined documentation habits, and the ability to work both independently and in a group, within defined procedures.

Core Responsibilities

• Perform upstream bioprocess workflows, including mammalian cell culture maintenance, per established protocols and cGMP standards
• Support and occasionally participate in downstream bioprocess workflows such as but not limited to basic supply preparations, formulations, and documentation
• Operate production equipment (pipettors, balances, biosafety cabinets, incubators, autoclaves, microscopes, centrifuges) accurately and safely
• Complete manual, cGDP-compliant documentation in batch records and forms with a high degree of accuracy
• Coordinate bioprocessing supply needs (e.g. raw material sourcing/pricing) and assist with planning for future productions.
• Collaborate with Process Development Team on technical transfer and experiment needs
• Contribute to the editing/updating of controlled process documentation as needed
• Mentor, train, and review the work and documentation of junior team members as needed

Required Skills and Experience

• Bachelor's degree in a relevant field (e.g. biology, cell biology, biochemistry, bioengineering) with 3+ years of directly relevant experience; or a master's degree with 1+ years of relevant experience; or an associate degree with a minimum of 5 years of relevant experience
• Significant, hands-on experience with aseptic mammalian cell culture techniques
• Broad working knowledge of stem cell culture processes
• Excellent organizational and communication skills, and the ability to manage substantial technical data, multiple priorities, and competing deadlines
• Strong attention to detail and document review skills to reliably produce audit-ready process documentation
• Proficiency with primary Microsoft Office Suite tools (Outlook, Microsoft Word, PowerPoint, Excel)
• Ability to work cooperatively in a controlled environment (ISO 5, 7, and 8) wearing clean room PPE for extended periods of time.
• Willingness to participate in a rotating weekend work and holiday schedule to perform primary cell culture maintenance tasks

Preferred

• Hands-on industrial experience in a cGMP-compliant environment
• Previous leadership experience in production-scale, aseptic mammalian cell culture
• Previous experience cooperating with and assisting research staff in a laboratory setting

To apply: Send a cover letter and resume to Sign in to view email with the subject line

"Bioprocess Associate 2 – Upstream."

Aruna Bio is an equal opportunity employer.